3,4 Typical signs of hyperthyroidism often are just the opposite and include tachycardia, heat sensitivity, and moist, oily skin. Common signs of hypothyroidism include lethargy, dry skin, brittle hair and fingernails, and cold temperature sensitivity. An underactive thyroid gland leads to hypothyroidism.īecause thyroid hormones affect various body systems, signs and symptoms associated with Graves’ disease can be wide-ranging and significantly influence a person’s overall well-being. When the body produces too much thyroid hormone, the condition is called hyperthyroidism. Controlling metabolism is important for regulating mood, weight, and mental and physical energy levels. 3-6 Thyroid hormone helps the body use energy, stay warm, and keep the brain, heart, muscles, and other organs functioning properly. 2 This gland releases the hormones thyroxine (T 4) and triiodothyronine (T 3), which control body metabolism. The thyroid, a butterfly-shaped gland located at the front of the neck, is an important organ of the endocrine system. The term Basedow’s disease is more commonly used in continental Europe in the United States, it is called Graves’ disease. He was unaware that Graves had described the same disease a few years earlier. 1 It is also referred to as Basedow’s disease-named after a German doctor, Karl Adolph von Basedow, who also described the disorder in 1840. Graves’ disease is named for the physician who first described the condition in Ireland in 1835-Robert J. Beta-blockers may be used to provide symptomatic relief. Treatments include radioactive iodine, antithyroid medications (propylthiouracil, methimazole), and surgery. The primary goals of treatment are to eliminate excess thyroid hormone and minimize the long-term consequences of the disease. If left untreated, Graves’ disease can cause a severe, life-threatening crisis (i.e., thyroid storm). The disorder can affect anyone at any age, but it is more common in women. The exact cause of Graves’ disease is not known. ABSTRACT: Graves’ disease is an autoimmune disorder that occurs when the immune system attacks the thyroid gland and causes it to produce too much thyroid hormone (hyperthyroidism).
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